In this review, we evaluate the potential and recent advancements in using artificial intelligence techniques to de-escalate loco-regional breast cancer therapy, with a special focus on surgical treatment after neoadjuvant systemic treatment (NAST).The increasing use and efficacy of NAST make the optimal loco-regional management of patients with pa
The Janus kinase 2 (JAK2)-driven myeloproliferative neoplasms (MPNs) are associated with clonal myelopoiesis, elevated risk of death due to thrombotic complications, and transformation to acute TRIPHASIC REACTIONAL myeloid leukemia (AML).JAK2 inhibitors improve the quality of life for MPN patients, but these approved therapeutics do not readily red
Transient receptor potential (TRP) channels are broadly implicated in the developmental programs of most tissues.Amongst these tissues, skeletal muscle and adipose are noteworthy for being essential in establishing systemic metabolic balance.TRP channels respond to environmental stimuli by supplying intracellular calcium that instigates enzymatic c
The world is currently dealing with the aftermath of the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in momentous MOISTURIZING HAIR AND BODY WASH changes, the likes of which had not been witnessed within the previous century.These adverse events and the resulting uncertainty have posed enormous challenges to organizations, and
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year.COVID-19 remains an important subject of intensive research owing Clothing Mens to its huge impact on economic and public health globally.Based on historical archives, t